Pickwick Club: posthumous papers

Q: Should we routinely screen for hypercapnia in sleep apnea patients before elective noncardiac surgery?

OHS is also known as Pickwickian syndrome, named for a character—a “fat boy” who is constantly falling asleep—in The Posthumous Papers of the Pickwick Club by Charles Dickens. Salient features of OHS are: Obesity (body mass index ≥ 30 kg/m • 2) Sleep-disordered breathing (most patients with • OHS are morbidly obese and have severe obstructive sleep apnea1) Chronic daytime alveolar hypoventilati...

Leptin, Obesity and Control of Breathing : the New Aventures of Mr Pickwick

Spanish version There are just two decades that respiratory disorders linked to obesity began to take an important place in medical publications. Nevetheless, fiction literature has largely anticipate (once again...) science: already in 1836, Charles Dickens drew in his novel "The posthumous paper of the Pickwick Club"1 what would be, certainly, the best characterization of an obese subject wit...

Posthumous reproduction.

Surgical Club of South West England—Abstracts of Papers

This first report of recurrent multiple inflammatory fibroid polyps occurred in three generations of a Devon family; in the grandmother first at the age of 59 years, in the mother first at the age of 35 years, both in Tiverton, and in the granddaughter first at the age of 22 years, three years after emigrating to New Zealand. Only one female in each generation has been affected, in a direct lin...

The Non-Coding RNA Journal Club: Highlights on Recent Papers

1 Department of Morphology, Pathology Oncology and Experimental Biology Section, University of Ferrara, Ferrara 44121, Italy; E-Mail: [email protected] 2 Laboratory for Technologies of Advanced Therapies, University of Ferrara, 44121 Ferrara, Italy 3 Institute for Integrative Biology of the Cell (I2BC), CEA, CNRS, Université Paris-Sud, 91198 Gif sur Yvette, France; E-Mail: daniel.gauthe...